Unexplained infertility is a term used by doctors when fertility tests fail to identify a specific reason for a couple's inability to conceive. This diagnosis is made only after both partners have undergone thorough fertility evaluations, which show no abnormalities. Statistics on the prevalence of unexplained infertility vary: some sources report it affects about 10% of couples trying to conceive, while others suggest the figure could be as high as 30%​. Usually, people dealing with unexplained infertility have been trying to conceive for a year (younger than 35) or 6 months (35 or older). Learn more about unexplained infertility from the doctors of the best infertility clinic in Kolkata.

Contributing factors to a normal pregnancy

A normal pregnancy relies on several key factors, which are evaluated during fertility testing:

  1. Uterine Health: No structural abnormalities or issues with the uterus.

  2. Ovulation: Regular and consistent ovulation cycles.

  3. Fallopian Tubes: Open and unobstructed fallopian tubes.

  4. Ovarian Reserve: Adequate egg count.

  5. Hormonal Balance: Proper levels of reproductive hormones produced by the brain.

  6. Semen Quality: Normal semen analysis, including sperm count and motility. 

Diagnosis of Unexplained Infertility

If the aforementioned factors are alright, doctors may recommend a comprehensive evaluation, as no single test can detect all potential irregularities causing infertility. Diagnosis of unexplained infertility is by exclusion of known causes of infertility. Additionally, some testing methods may miss mild abnormalities. As per the doctors of the best infertility solution clinic in Kolkata, a thorough fertility assessment should include:

  1. Complete Medical and Sexual History: To identify any underlying issues or factors that might affect fertility.

  1. Physical Examination: To check for any physical conditions that could impact reproductive health.

  1. Blood Tests: To evaluate hormone levels essential for reproduction.

  1. Assessment of Reproductive Organs: Using ultrasound or advanced imaging tests like hysterosalpingogram or laparoscopy to examine the ovaries, fallopian tubes and uterus. Laparoscopy serves as a minimally invasive diagnostic tool to examine and treat endometrial lesions. It is particularly effective in the case of minimal to mild endometriosis.

  1. Semen Analysis: To assess sperm count and motility.

  1. Ovarian Reserve Testing: To determine the quantity and quality of the eggs.

  1. Ovulation Check: To ensure regular ovulation is occurring.

If a fertility specialist or obstetrician conducts these comprehensive tests and still finds no cause, they may call it unexplained infertility. In case the test reports are more than 6 months old, doctors may recommend a repeat test.

Treatments for Unexplained Infertility

When infertility lacks a clear cause, your doctor will likely propose treatment tailored to your fertility test results, their expertise on similar cases. Both your and your partner’s age also factor in.

Common treatments generally fall into these categories:

  • Assisted Reproductive Technology (ART): According to the doctors who offer the best fertility treatment services in Kolkata, ART is a kind of fertility treatment that involves fertilization processes happening in a lab, such as Intrauterine Insemination (IUI) and In Vitro Fertilization (IVF). IUI involves washing and concentrating sperm before injecting it into your uterus during ovulation. IVF involves the creation of embryos in a lab with the eggs and sperm (or donor sperm) and then transferring the embryo to your uterus. IVF may include Intracytoplasmic Sperm Injection (ICSI), where sperm is injected directly into the egg, which is particularly helpful when sperm quality is a potential issue.


  • Lifestyle Changes: Lifestyle factors play a role in infertility, so adopting healthy habits can aid conception. Recommendations may include avoiding smoking, alcohol and recreational drugs, maintaining a healthy weight, eating a balanced diet, exercising regularly for at least 30 mins each day, limiting caffeine intake and managing stress.


  • Improved Timing of Intercourse: Identifying the optimal window in your menstrual cycle for conception is crucial. Your doctor may assist in pinpointing this window through methods like temperature tracking, cycle charting or ovulation prediction kits.

Extended Attempts: Some doctors may advise patience, allowing for longer attempts at conception before pursuing treatment. While it can be challenging, especially with hopes of starting a family, sometimes issues are resolved without intervention.

Initiating an early consultation with the doctors of the best infertility clinic in Kolkata can swiftly pinpoint potential concerns and steer couples toward state-of-the-art reproductive solutions, facilitating their journey to parenthood.